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AAOS Now, February 2016

Biofilm a Unique Factor in Orthopaedic Infection

Kenneth L. Urish, MD, PhD; Nicholas John Giori, MD, PhD; the AAOS Biomedical Engineering Committee

Infection is one of the broadest, most challenging problems in orthopaedic surgery. In total knee arthroplasty (TKA), the infected implant is a leading cause for revision surgery. Avoiding infection in the management of open fractures is one of the core principles of orthopaedic residency training. Chronic osteomyelitis, especially in children, can develop a number of sequelae and was associated with high mortality before the advent of antibiotics.