Morton neuroma, or interdigital neuritis, is a compression neuropathy with associated perineural fibrosis that is caused by entrapment of the interdigital nerve near the distal edge of the transverse intermetatarsal ligament. The second and third interdigital nerves in the forefoot are most commonly involved. In one series, Morton neuroma was found to occur at an average age of 55 years (range, 29 to 81 years), predominantly in women.1 Most patients can be treated nonsurgically with shoe wear modification, plantar pad placement, nonsteroidal antiinflammatory drugs, Achilles stretching, and, on a limited basis, cortisone injection. Surgical treatment should be reserved for select patients with a clear diagnosis. Surgery is done to decompress the entrapped interdigital nerve by transecting the intermetatarsal ligament, releasing or resecting the interdigital nerve itself, and/or releasing any nerve branches causing tethering, thereby allowing the nerve to move more proximally away from the weight-bearing portion of the forefoot.